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Impotence: Treatment Development and Outlook
Due to the high prevalence rate of erectile dysfunction, the responsibility of ED management has been shifted to the primary care physicians. As a result, primary care physicians now need to add questions about sexual functioning and satisfaction during the initial patient workup. Patients with ED is treated by the primary care physician, or referred to other health care professionals, depending on the problem presented. Treatment and management of individuals with ED includes patient education, particularly focusing on general sex education and sexually transmitted diseases. Counseling and providing an appropriate treatment of impotence, basing on its main cause are also included in the program. Up to 85% of impotence cases are caused by medical or physical problems, and so, it is essential that a healthy lifestyle and avoidance or moderation in smoking and alcohol are emphasized
Advances in suppositories, injectable medications, implants, and vacuum devices have stretched out the options for men seeking treatment for ED. The medical and surgical advancement in treating erectile dysfunction has helped increase the number of men to seek consult and treatment. Gene therapy for ED is now being tested in several centers in US, and may offer a long-lasting therapeutic approach for ED.
Most research now is focused on using organic sources of treatments and enhancing of the existing ones. Organic sources such as watermelon are being looked into as alternative means to treat impotence. You can read this at http://www.webmd.com/erectile-dysfunction/news/20080701/watermelon-a-natural-viagra. Institutes such as the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) sponsors programs that aim at understanding the causes of erectile dysfunction and at finding treatments to reverse its effects. NIDDK’s Division of Kidney, Urologic, and Hematologic Diseases supported the researchers who developed Viagra and up to this time, it continuously supports basic research regarding the mechanisms of erection. In addition, continuous support is given in the research of diseases that impair the normal body functions at the cellular and molecular levels, such as diabetes and high blood pressure. These are signs of a growing awareness and acceptance of the problem ED in the society.
History of Treatments on Impotence
Before urologists recognized the physical nature of impotence, treatments generally fell into three categories—aphrodisiacs, surgery or transplants, and mechanical treatments.
Innumerable substances called aphrodisiacs have been used to increase sexual performance. Oysters, lobsters, eggs, and spices are some known aphrodisiacs. Noteworthy to mention, these sources are now recognized to do nothing more than irritate the genital organs. The user interprets this irritation as an increased sexual sensitivity, thereby creating the impression of increased performance.
In the 1880s, French physiologist Charles Edouard Brown-Sequard injected himself with an extract from a dog’s testicles that he claimed to have made him smarter, stronger, and more virile. In the 1920s, Eugen Steinach pioneered a surgical treatment of impotence called vasectomy. In the early twentieth century, Swiss professor Paul Niehans treated men with testicular cell injections. Another surgeon, Dr. Leo Stanley removed the testicles of recently executed prisoners and transplanted them into impotent prisoners. When the supply ran low, he substituted them with goat, ram, boar, and deer testicular tissues. It remains unclear whether any of these early attempts to treat impotence through the use of human or animal testicular tissue have actually worked. Most of the researchers mentioned eventually fell into disrepute.
In the US, Dr. John R. Brinkley broadcasted male impotence cures in his radio programs. He recommended expensive goat gland implants and “mercurochrome” injections as the paths to restore male virility. His medical license was revoked, and his radio license was not renewed.
For mechanical devices, many types of splints have been used to treat impotence, including hollowed-out antlers and horns. Although these initial attempts failed, penile prostheses are recently proven to be particularly reliable. During the 70s, surgeons began providing patients with inflatable penile implants.
The use of medications started in the ninth century until the sixteenth century. Muslim physicians and pharmacists in the medieval Islamic world were the first to prescribe medications for ED. They developed several methods of therapy, which include a single or a combination of drugs and food. Most were oral medications, though a few patients were also treated through topical and transurethral means. In 1983, modern drug therapy for ED made a significant exploit when British physiologist Giles Brindley, Ph.D. dropped his trousers and demonstrated to a shocked American Urological Association audience his phentolamine-induced erection. The drug he injected into his penis was a vasodilator, and the mechanism of action was muscle relaxation. This discovery established the fundamentals for the later development of orally-effective drug therapies. In 1998, a breakthrough in medicine occurred with the introduction of Viagra in the market as an effective drug against erectile dysfunction. The drug was originally researched for its beneficial effects in chronic increase in blood pressure and chest pains. A few years later, vardenafil and tadalafil are introduced as effective erections drugs.
Physiology of Erection
How Does Erection Occur?
During sexual arousal, the genital organs relax and become engorged with blood. In men, transmission of nerve impulses from the brain to the penis causes an increased blood flow to the male organ. This sudden influx of blood expands the muscles of the penis and produces an erection by straightening and stiffening its muscles. Continued sexual arousal maintains a higher rate of blood flow into the genital organ and limits the blood flow out of it, causing firmness of the penis. After ejaculation or sexual climax, the excess blood drains out, and the penis returns to its non-erect size and shape.
In women, the enlargement of the clitoris and the surrounding tissues are comparable to the erection of the penis. Physiology of orgasm in female can be categorized in four distinct stages. The first stage is the excitement stage. The heart and respiration rates increase, and the blood pressure goes up. The clitoris swells and the vagina begins to lubricate itself. The blood vessels narrow, and when this is coupled with an increased heart rate, flushing of the skin occurs. Breasts may swell and the nipples harden and taut. The entire excitement process can happen in a matter of seconds from the onset of sexual stimulation. Stage two is called the plateau. The body continues to experience the aforementioned changes. Further stimulation will cause the inner lips of the vagina to darken due to the increased blood flow to the genital area. By the end of this stage, the pulse and respiration rates have peaked, pushing the body into the third stage. The third stage is the actual orgasm, when the clitoris retracts and the vagina tightens and lengthens. Spasms of the vaginal and anal muscle occur rhythmically like wavelike contractions that move from the top of the uterus to the cervix. Other changes related to the female orgasm include muscle contractions throughout the body, more notably in the neck, pelvis, arms and legs. The fourth and final stage of the physiology of orgasm is often referred to as the resolution stage. The excess blood will drain from the genital area, and the clitoris returns to its normal size. The body returns to its previous, non-stimulated state.
The Emergence of Sexual Dysfunctions: An Introduction to Impotence
Sexual dysfunction, also termed impotence, is one of the most prevalent conditions seen in the population, most particularly among the older males. A condition which may have a physical or a psychological origin, impotence continues to be one of the most “humiliating and demeaning” health concerns worldwide.
Impotence is outstandingly prevalent as the age advances. Roughly, in the United States alone, 18 to 30 million American males are likely affected by impotence. A survey was conducted by the Male Aging Study (MMAS) among men ages 40 to 70 years, with a purpose to determine the prevalence of male impotence. Astoundingly 52% of the participants revealed some erectile dysfunctions of various magnitude and extent. In 2007, approximately 10.4% of men, ages 18 to 59 were unable to attain or sustain an erection, as revealed by the National Health and Social Life Survey. Both surveys showed a close association between aging and impotence, which support the idea that this condition is indeed physical in origin, and not purely psychological.
According to MMAS, 17% of men whose ages range from 40 to 70 years have mild cases of erectile dysfunction. Around 25% of men in this age group report moderate manifestations of male impotence. A cause for concern is the tripling percentage of cases with complete erectile dysfunction. A complete erectile dysfunction is described as the total inability to initiate or sustain erections during sexual stimulations with the absence of nocturnal erections.
It was once thought that impotence exclusively occurs in males, but researchers revealed that women, too can suffer from impotence. What’s more, female impotence is not as rare as we used to think. According to the California Association of Marriage and Family Therapists, 40% of women have cases of female sexual dysfunction or FSD. Undeniably, the prevalence of impotence is eminent and spans both genders and off all different age groups.
According to Abraham Maslow’s Hierarchy of Needs, sexual satisfaction is a physiological need – a fundamental and basic need for a human being to survive. Without a satisfying sexual relationship and expression, you cannot fully attain your other needs as a person. These include security, love and self – esteem. This might probably explain why people with impotence are often insecure with poor insight of their worth as a person. Without a doubt, the interference of the normal sexual activities has a great impact on the quality of your quality of life. Impotence may not sound as grave as the other medical conditions we know, but it can greatly incapacitate one’s psychological and emotional state. Sexual dysfunctions may not be as severe as the other diseases but it is a condition that needs medical help and intervention.
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